Development and optimisation of microbiologically or enzymatically catalysed processes

Process development is a logical consequence of obtaining an interesting biocatalyst, be it a bacterium, fungus or an enzyme isolated from one. Our laboratories are equipped with a system of small scale bioreactors perfectly suited for performing such tasks with high throughput (BioFlo 115, New Brunswick Scientific). These devices allow researchers to minimize the influence of external parameters and focus on process variables. Performing simultaneous runs in strictly controlled environment enables screening for significant factors, both of physical and chemical nature, which are to be further optimized. A properly performed optimization has often proved to be the key on the way to applicative viability of a bioprocess. With cutting-edge analytical equipment available at WCAT, various responses to changes in process variables can be considered.